Must Knows on Neuropharmacology of Antiepileptic Drugs

A study guide and reviewer on must knows on neuropharmacology intended for nursing, pharmacology and medicine students. Valproate may enhance GABA transmission in specific circuits and blocks voltage-dependent sodium channel. Pregabalin increases neuronal GABA glutamic acid decarboxylase and increases neuronal calcium currents by binding of
alpha 2 delta subunit of the voltage gated calcium channel.