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Contents
Chapter 01: Cellular Biology.......................................................................................................................... 4
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases ...................................... 31
Chapter 04: Genes and Genetic Diseases ................................................................................................... 44
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases........................................................... 55
Chapter 06: Epigenetics and Disease .......................................................................................................... 63
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
Chapter 08: Adaptive Immunity .................................................................................................................. 83
Chapter 09: Alterations in Immunity and Inflammation............................................................................. 95
Chapter 10: Infection ................................................................................................................................ 108
Chapter 11: Stress and Disease ................................................................................................................. 117
Chapter 12: Cancer Biology....................................................................................................................... 124
Chapter 13: Cancer Epidemiology............................................................................................................. 137
Chapter 14: Cancer in Children ................................................................................................................. 143
Chapter 15: Structure and Function of the Neurologic System ................................................................ 148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ............................................... 159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ............... 174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ........................... 199
Chapter 20: Alterations of Neurologic Function in Children..................................................................... 206
Chapter 21: Mechanisms of Hormonal Regulation................................................................................... 213
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
Chapter 24: Structure and Function of the Reproductive Systems .......................................................... 239
Chapter 25: Alterations of the Female Reproductive System .................................................................. 249
Chapter 26: Alterations of the Male Reproductive System ...................................................................... 259
Chapter 27: Sexually Transmitted Infections ............................................................................................ 265
Chapter 28: Structure and Function of the Hematologic System ............................................................. 273
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ......................................... 283