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NR 283 PATHOPHYSIOLOGY EXAM 2 STUDY GUIDE


NR 283 PATHOPHYSIOLOGY EXAM 2 STUDY GUIDE
Chapter 8: Skin Disorders
1.Viral infections
a.Take antiviral to reduce viral shedding (can’t proliferate)
2.Autoimmune skin disorders
a.Shingles
b.Pemphigus  blisters
i.2 forms = vulgaris & foliaceus
ii.Antibodies disrupt the cohesion between the epidermal cells causing blisters to form
iii.Treatment = systemic glucocorticoids such as prednisone & other immunosuppressants
3.Psoriasis
a.A chronic inflammatory skin disorder caused by abnormal T cell activation
b.Cells are shedding epithelium a lot faster than they should (increased mitosis) = flakiness
c.lesions found on face, scalp, elbows & knees
d.Treatment = glucocorticoids, tar preparations & antimetabolites
4.HSV I and HSV II (Herpes Simplex Virus I & II)
a.Type I = cold sores & fever blister
b.Type II = genital
c.Spread by direct contact
5.HPV (Human Papilloma Virus)
a.Types 1-4 = plantar warts
b.Types 6 & 11 = genital warts
c.Predisposing factor: Cancer  Cervical

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