Pharmacology HESI Review
Cardiac Drugs/Diuretics
• Digoxin (Lanoxin) – positive inotrope (increases force of contraction); negative chronotrope (decreases heart rate). How do you assess for this? (Always take AP for a full minute!)
• Client with long hx of daily digoxin and furosemide (Lasix) use; creates a high risk for dig toxicity (Lasix can cause hypokalemia, which can lead to dig toxicity)
• Digoxin taken with dronedarone (Multaq), which is another antidysrhythmics, can significantly increase blood levels of digoxin and further increase the effects.
• Digoxin toxicity – know normal digoxin level (0.5 – 2 ng/mL); serum potassium (K+) level (3.5 to 5.0 mEq/L); low potassium or magnesium levels may increase risk for digoxin toxicity; S/S of dig toxicity
include anorexia, bradycardia, headache, dizziness, confusion, nausea, and visual disturbances (blurred vision, yellow vision, and/or halo vision); hold digoxin if AP less than 60.